InsightRx is pioneering the future of precision medicine. We envision a world in which all medications work as intended, maximally effective and safe. Our platform leverages quantitative pharmacology and artificial intelligence to optimize therapeutic outcomes across the spectrum of drug development and patient care. It has benefited close to 2 million patients across the U.S. and Europe.Life Sciences: Accelerating drug development with AI-powered PK/PD modeling and decision support. This includes building AI agents that streamline pharmacometric workflows, enabling scientists to run complex analyses, grounded in clinical trial data.Healthcare Delivery: Enabling precision dosing and individualized treatment at the point of care. Our focus here includes developing robust retrieval-augmented generation (RAG) pipelines to support clinicians with real-time, context-aware dosing guidance.AI is central to our next phase of growth. We're building agentic AI systems that enhance how clinical pharmacologists, pharmacists, and translational scientists conduct modeling and make therapeutic decisions.About the RoleWe are looking for a Principal AI Engineer to lead the design and implementation of advanced AI systems—particularly in the areas of agentic AI and production-grade LLM applications. This role blends deep technical expertise with strategic problem-solving to build intelligent systems that are robust, efficient, and impactful.Key ResponsibilitiesArchitect agentic AI systems that solve complex business problems without unnecessary complexityLead prompt engineering initiatives and develop advanced prompting strategies for production useGuide decisions on AI model selection, deployment, and optimizationEstablish best practices for AI system reliability, observability, and performanceProduction AI DevelopmentBuild and maintain production-grade LLM applications using modern Python frameworksImplement robust queuing systems (e.g., SQS, Redis) for asynchronous workloadsDesign fault-tolerant systems that gracefully handle LLM errors and outagesDevelop testing strategies for non-deterministic AI componentsTechnical LeadershipMentor engineers on AI best practices and architectural patternsCollaborate with cross-functional teams to translate business needs into scalable technical solutionsDrive adoption of modern agentic frameworks and tools across the organizationContribute to AI roadmap planning and technical strategyQualificationsTechnical ExpertisePrompt Engineering: Advanced experience crafting, optimizing, and productionalizing LLM promptsAgentic AI: Deep understanding of agentic design patterns and orchestration strategiesLLM Operations: Hands-on experience deploying and maintaining LLM-based systems in productionModern Python: Expert-level proficiency in Python and its async ecosystemAI Frameworks: Experience with tools like LangGraph, PydanticAI, or similarModel Knowledge: Familiarity with Claude, GPT-4, and other foundation modelsDistributed Systems: Strong grasp of queuing systems and asynchronous task handlingExperience & EducationBSc. in Computer Science, Machine Learning, or related field—or equivalent practical experience5+ years of experience building and scaling production AI/ML systemsGenuine interest in applying AI to clinical and scientific domainsWhat We're Looking ForTechnical MindsetPragmatic approach to AI—knows when to build vs. when to simplifyStrong debugging and troubleshooting capabilitiesComfort with evaluating and A/B testing model-driven featuresLeadership QualitiesAbility to mentor and scale an engineering teamStrong written and verbal communication skillsExperience leading complex initiatives from ideation to deploymentCultural FitIntellectual curiosity and willingness to learn domain-specific conceptsPassion for building AI systems that have real-world healthcare impactThrives in dynamic, fast-evolving technical environmentsWhat You’ll BuildScalable agentic AI systems powering the Apollo-AI platformPrompt engineering pipelines and LLM performance evaluation toolsFault-tolerant AI infrastructure for healthcare and life sciences applicationsInternal frameworks to accelerate cross-team AI adoptionJoin InsightRx to shape the future of AI in medicine. You’ll be at the forefront of building intelligent systems that accelerate drug development and improve patient care.Create a Job AlertInterested in building your career at InsightRX? Get future opportunities sent straight to your email.Accepted file types: pdf, doc, docx, txt, rtfEnter manuallyAccepted file types: pdf, doc, docx, txt, rtfHave you included your LinkedIn profile in your resume? If not, please include here *Are you legally authorized to work in the United States or Canada without the need for current or future sponsorship? * Select...Are you willing to undergo a background check, in accordance with local law/regulations? * Select... #J-18808-Ljbffr